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Hepatitis C Elimination in NSW: Monitoring and Evaluation Report, 2024

This report evaluates progress towards hepatitis C elimination in NSW, aligning with state, national, and global elimination strategies. It assesses trends in testing, treatment, and prevention measures, as well as hepatitis C incidence, morbidity, and mortality. Each objective has a series of measurable indicators for monitoring progress, including a set of specific targets that evaluate service coverage and impact. The aim of this report is to describe hepatitis C elimination targets, objectives, and indicators, and the level of progress made in NSW.

Key findings
  • The initial eight years of the direct-acting antiviral (DAA) era in NSW have shown considerable progress towards hepatitis C elimination goals, particularly in reducing incident infections and hepatitis C-related mortality.
  • High uptake of curative DAA therapy has not led to increased risk behaviours, with needle and syringe program coverage and testing levels remaining high among people who inject drugs.
  • Stable risk behaviour combined with high DAA therapy uptake has produced marked declines and hepatitis C prevalence and incidence of new hepatitis C infections.
  • The burden of advanced liver disease, which was escalating before the introduction of new therapies, is now declining.
  • Treatment uptake has been remarkably equitable, with indications of higher uptake among higher-risk and marginalised populations.
  • Despite overall progress, there are still gaps in service delivery with evidence of lower screening and diagnosis of hepatitis C in rural areas.
  • Ongoing efforts are needed to address persistent stigma and discrimination, enhance prevention strategies, and maintain high levels of testing and treatment to achieve elimination goals.
  • The framework for ongoing evaluation has been established, providing a foundation for monitoring progress and guiding future efforts towards hepatitis C elimination in NSW.