Malaria is a health concern globally, and in particular amongst our nation’s closest regional neighbours. Despite global initiatives to eradicate malaria, it remains responsible for almost half a million deaths annually. Our team works with clinical and experimental collaborators globally with the aim of advancing our knowledge of malaria and reducing the burden of disease. The team relies on quantitative and analytical thinking to analyse and interpret clinical and experimental data. Our quantitative and modelling approaches enable a unique and dynamic understanding of the processes of malaria transmission, infection, immunity and drug treatment. With these tools and broad collaborative initiatives, our group is working towards a deep understanding of malaria and how to improve malaria control.