The goal of the research groups which are led by Professor Lloyd is to understand the cellular and molecular basis of host responses in human infectious diseases. In particular, the groups are focussed on studies of the pathogenesis of hepatitis C infection, and the characteristics of the host response to other infections including Epstein-Barr virus, Ross River virus and Coxiella burnetii - the causative agent of Q fever.
The scope of the research extends from laboratory studies of the basic biology of genes relevant to disease pathogenesis through to clinical and epidemiological studies in humans, including in prospective cohort studies and clinical trials. The laboratory-based research includes next generation sequencing of viruses, as well as cellular and molecular immunology techniques, including multi-colour flow cytometry, neutralisation assays, enzyme-linked immunospot (ELISpot) and mutliplex cytokine detection assays. In addition, the research includes in vitro studies in cell culture systems as well as tissue-based studies in human samples and in animal models of disease.
Broad Research Areas:
Immunology, Virology, Infectious Diseases, Inflammation, Pathology
MB BS Syd, MD UNSW, FRACP
Society Memberships & Professional Activities:
American Association of Immunologists; Australasian Society for Infectious Diseases; Australasian Society for Immunology; Australasian Society for HIV Medicine; Australian Centre for Hepatitis Virology
Specific Research Keywords:
Hepatitis C, Anti-viral immunity, T cells, B Cells, Cytokines, Chemokines, Post-infective fatigue states