Nick completed his Bachelor’s Degree in Medical Science at the Australian National University in 2016. During his studies, he focused on immunology and genetics, also completing a Minor in Science Communication.
In 2017, Nick joined the VISP group as an Honours Student under the supervision of Professor Andrew Lloyd, Dr Auda Eltahla and Associate Professor Nicodemus Tedla, in a project to understand the immunodominance of B cell epitopes in primary hepatitis C virus (HCV) infection. From 2018, Nick has continued his studies with VISP and is now studying his PhD under the supervision of Dr Rowena Bull, Dr Auda Eltahla and Associate Professor Nicodemus Tedla. His current project includes understanding anti-HCV antibody epitope targets and B cell gene usage, examining BCR lineages and the pathway towards neutralising antibody development, and investigating the origin of long-lived plasma and memory cells.
Abayasingam A; Balachandran H; Agapiou D; Hammoud M; Rodrigo C; Keoshkerian E; Li H; Brasher NA; Christ D; Rouet R; Burnet D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Stella AO; Fichter C; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Tea F; Pilli D; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, 2021, 'Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection', Cell Reports Medicine, pp. 100228, http://dx.doi.org/10.1016/j.xcrm.2021.100228
Brasher NA; Eltahla AA; Underwood A; Boo I; Rizzetto S; Walker MR; Rodrigo C; Luciani F; Maher L; Drummer HE; Tedla N; Lloyd AR; Bull RA, 2020, 'B cell immunodominance in primary hepatitis C virus infection', Journal of Hepatology, vol. 72, pp. 670 - 679, http://dx.doi.org/10.1016/j.jhep.2019.11.011
Walker MR; Leung P; Eltahla AA; Underwood A; Abayasingam A; Brasher NA; Li H; Wu BR; Maher L; Luciani F; Lloyd AR; Bull RA, 2019, 'Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies', Scientific Reports, vol. 9, pp. 13300, http://dx.doi.org/10.1038/s41598-019-49454-w
Wu BR; Eltahla AA; Keoshkerian E; Walker MR; Underwood A; Brasher NA; Agapiou D; Lloyd AR; Bull RA, 2019, 'A method for detecting hepatitis C envelope specific memory B cells from multiple genotypes using cocktail E2 tetramers', Journal of Immunological Methods, vol. 472, pp. 65 - 74, http://dx.doi.org/10.1016/j.jim.2019.06.016
Underwood AP; Walker MR; Brasher NA; Eltahla AA; Maher L; Luciani F; Lloyd AR; Bull RA, 2018, 'Understanding the determinants of BnAb induction in acute HCV infection', Viruses, vol. 10, http://dx.doi.org/10.3390/v10110659