Dr Sarah Sasson

Sasson SC; Slevin SM; Cheung VTF; Nassiri I; Olsson-Brown A; Fryer E; Ferreira RC; Trzupek D; Gupta T; Al-Hillawi L; Issaias ML; Easton A; Campo L; FitzPatrick MEB; Adams J; Chitnis M; Protheroe A; Tuthill M; Coupe N; Simmons A; Payne M; Middleton MR; Travis SPL; Fairfax BP; Klenerman P; Brain O, 2021, 'Interferon-Gamma–Producing CD8⁺ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor–Colitis', Gastroenterology, vol. 161, pp. 1229 - 1244.e9, http://dx.doi.org/10.1053/j.gastro.2021.06.025

Hargreaves CE; Salatino S; Sasson SC; Charlesworth JEG; Bateman E; Patel AM; Anzilotti C; Broxholme J; Knight JC; Patel SY, 2021, 'Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders', Journal of Clinical Immunology, vol. 41, pp. 1315 - 1330, http://dx.doi.org/10.1007/s10875-021-01050-2

Abayasingam A; Balachandran H; Agapiou D; Hammoud M; Rodrigo C; Keoshkerian E; Li H; Brasher NA; Christ D; Rouet R; Burnet D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Stella AO; Fichter C; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Tea F; Pilli D; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, 2021, 'Long-term persistence of RBD⁺ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection', Cell Reports Medicine, vol. 2, pp. 100228, http://dx.doi.org/10.1016/j.xcrm.2021.100228

van der Linde R; Smith S; Sasson SC; Brown D; Tegg E, 2021, 'Use of multidimentional flow cytometry plots to improve measurable residual disease monitoring of acute myeloid leukaemias', Pathology, vol. 53, pp. S46 - S46, http://dx.doi.org/10.1016/j.pathol.2021.06.096

Sasson SC, 2021, 'Autoimmune toxicities of T cell checkpoint inhibitors', Pathology, vol. 53, pp. S16 - S16, http://dx.doi.org/10.1016/j.pathol.2021.05.058

Sasson SC; Zaunders JJ; Nahar K; Munier CML; Fairfax BP; Olsson-Brown A; Jolly C; Read SA; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Payne MJ; Cheung VTF; Gupta T; Klenerman P; Long GV; Brain O; Menzies AM; Kelleher AD, 2020, 'Mucosal-associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy-related colitis in a pathology distinct from ulcerative colitis', Clinical and Experimental Immunology, vol. 202, pp. 335 - 352, http://dx.doi.org/10.1111/cei.13502

Cheung VTF; Gupta T; Olsson-Brown A; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Tuthill M; Protheroe AS; Chitnis M; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?', British Journal of Cancer, vol. 123, pp. 207 - 215, http://dx.doi.org/10.1038/s41416-020-0882-y

Sasson SC; Gordon CL; Christo SN; Klenerman P; Mackay LK, 2020, 'Local heroes or villains: tissue-resident memory T cells in human health and disease', Cellular and Molecular Immunology, vol. 17, pp. 113 - 122, http://dx.doi.org/10.1038/s41423-019-0359-1

Cheung VTF; Gupta T; Olsson-Brown A; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'P272 Immune checkpoint inhibitor-related colitis assessment and prognosis: can inflammatory bowel disease scoring point the way?', Journal of Crohn's and Colitis, vol. 14, pp. S286 - S288, http://dx.doi.org/10.1093/ecco-jcc/jjz203.401

Cheung VT; Gupta T; Olsson-Brown AC; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes-Bellido E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'Su1185 IMMUNE CHECKPOINT INHIBITOR-RELATED COLITIS ASSESSMENT AND PROGNOSIS: CAN UCEIS, MAYO AND NANCY INDEX SCORING POINT THE WAY?', Gastroenterology, vol. 158, http://dx.doi.org/10.1016/s0016-5085(20)32033-3

Sasson SC; Corbett A; McLachlan AJ; Chen R; Adelstein SA; Riminton S; Limaye S, 2019, 'Enhanced serum immunoglobulin G clearance in myotonic dystrophy-associated hypogammaglobulinemia: A case series and review of the literature', Journal of Medical Case Reports, vol. 13, http://dx.doi.org/10.1186/s13256-019-2285-3

Sasson SC; Cheung VTF; Gupta T; Zaunders JJ; Nahar K; Munier CM-L; Olsson-Brown A; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Long GV; Menzies AM; Kelleher A; Payne M; Fairfax B; Middleton MR; Klenerman P; Brain O, 2019, 'Tissue-based activation of mucosal-associated invariant T (MAIT) cells in combination ipilimumab and nivolumab checkpoint inhibitor (CI) colitis', Annals of Oncology, vol. 30, pp. v530 - v530, http://dx.doi.org/10.1093/annonc/mdz253.128

Deenick EK; Morey A; Danta M; Emmett L; Fay K; Gracie G; Ma CS; Macintosh R; Smith SABC; Sasson SC; Sewell WA; Cowley M; Tangye SG; Kelleher AD; Phan TG, 2018, 'Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency', Journal of Clinical Immunology, vol. 38, pp. 159 - 162, http://dx.doi.org/10.1007/s10875-018-0477-z

Sasson SC; Russo R; Chung T; Chu G; Hunyor I; Williamson J; Murad A; Kane A; Riminton S; Limaye S, 2017, 'Cardiac magnetic resonance imaging-indeterminate/negative cardiac sarcoidosis revealed by ¹⁸F-fluorodeoxyglucose-positron emission tomography: Two case reports and a review of the literature', Journal of Medical Case Reports, vol. 11, http://dx.doi.org/10.1186/s13256-017-1453-6

Koelsch KK; Rasmussen TA; Hey-Nguyen WJ; Pearson C; Xu Y; Bailey M; Marks KH; Sasson SC; Taylor MS; Tantau R; Obeid S; Milner B; Morrissey O; Pinto AN; Suzuki K; Busch MP; Keating SM; Kaiser P; Yukl S; Wong JK; Hiener BM; Palmer S; Zaunders J; Post JJ; Chan DJ; Avery S; Milliken ST; Kelleher AD; Lewin SR; Cooper DA, 2017, 'Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals', Journal of Acquired Immune Deficiency Syndromes, vol. 75, pp. 328 - 337, http://dx.doi.org/10.1097/QAI.0000000000001381

Sasson SC; Davies S; Chan R; Davies L; Garsia R, 2016, 'Cerebral toxoplasmosis in a patient with myasthenia gravis and thymoma with immunodeficiency/Good's syndrome: A case report', BMC Infectious Diseases, vol. 16, http://dx.doi.org/10.1186/s12879-016-1801-y

Anderson S; Sasson SC; Lee FJ; Cooper W; Larsen S; Garsia R, 2016, 'Episodic fevers and vasodilatory shock mimicking urosepsis in a patient with HIV-associated multicentric Castleman's Disease: A case report', BMC Infectious Diseases, vol. 16, http://dx.doi.org/10.1186/s12879-016-1378-5

Sasson SC; McGill K; Wienholt L; Carr A; Brown DA; Kelleher AD; Breit SN; Sewell WA, 2015, 'Comparison of the Freelite serum free light chain (SFLC) assay with serum and urine electrophoresis/immunofixation and the N Latex FLC assay', Pathology, vol. 47, pp. 564 - 569, http://dx.doi.org/10.1097/PAT.0000000000000316

Sasson SC; Smith SA; Qiu MR; Stone ECA; Sewell WA, 2015, 'Monoclonal precursor T-cell infiltrate in recurrent thymoma: a case report', Pathology, vol. 47, pp. 375 - 377, http://dx.doi.org/10.1097/PAT.0000000000000257

Sasson SC; McGill K; Wienholt L; Carr A; Brown D; Kelleher AD; Breit SN; Sewell WA, 2015, 'Retrospective audit of the freeliteTM serum free light chain (SFLC) assay: testing patterns, concordance with serum and urine electrophoresis/immunofixation and correlation with the N latex FLC assay', Pathology, vol. 47, pp. S94 - S94, http://dx.doi.org/10.1097/01.pat.0000461601.28805.d5

Koelsch KK; Hey-Cunningham WJ; Sasson SC; Pearson C; Bailey M; Marks KH; Hiener BM; Palmer S; Zaunders JJ; Post JJ; Milliken ST; Kelleher AD; Cooper DA; Xu Y, 2015, 'Allogeneic bone marrow transplantation in two HIV-1 infected patients shows no detectable HIV-1 RNA or DNA, and a profound reduction in HIV-1 antibodies', Pathology, vol. 47, pp. S55 - S55, http://dx.doi.org/10.1097/01.pat.0000461459.26902.eb

Sasson S; Smith S; Sewell WA; Morey A; Danta M; Emmett L; Kelleher AD; Fay K; Phan T, 2014, 'MONOCLONAL B-CELL POPULATION OF INDETERMINANT MALIGNANT POTENTIAL IN THE SETTING OF ATYPICAL CVID ASSOCIATED WITH LYMPHADENOPATHY AND SPLENOMEGALY', INTERNAL MEDICINE JOURNAL, vol. 44, pp. 33 - 33, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342722800109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sasson SC; Kelleher AD, 2014, 'Site-specific host gene modification by zinc finger nucleases: pointing the way to drug free control of HIV-1?', Clinical and Translational Immunology, vol. 3, http://dx.doi.org/10.1038/cti.2014.12

Sasson SC; Oon A; Chagantri J; Brew BJ; Carr A, 2013, 'Posterior reversible encephalopathy syndrome (PRES) in an HIV-1 infected patient with disseminated varicella zoster virus: a case report', BMC Infectious Diseases, vol. 13, pp. 396 - 396, http://dx.doi.org/10.1186/1471-2334-13-396

Sasson SC; Zaunders J; Seddiki N; Mcbride K; Koelsch KK; Merlin KM; Smith DE; Cooper DA; Kelleher AD; Bailey MR, 2012, 'Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection', PLoS One, vol. 7, pp. e31148, http://dx.doi.org/10.1371/journal.pone.0031148

Seddiki N; Sasson SC; Santner-Nanan B; Munier M; Van Bockel DJ; Ip S; Marriott D; Pett SL; Nanan R; Cooper DA; Zaunders J; Kelleher AD, 2009, 'Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease', European Journal of Immunology, vol. 39, pp. 391 - 403, http://dx.doi.org/10.1002/eji.200838630

Sasson SC; Zaunders J; Kelleher AD, 2006, 'The IL-7/IL-7 receptor axis: understanding its central role in T-cell homeostatis and the challenges facing its utilization as a novel therapy. 2006;7:1571-1582.', Current Drug Targets, vol. 7, pp. 1571 - 1582, http://dx.doi.org/10.2174/138945006779025365

Zaunders J; Ip S; Munier CM; Munier M; Kaufmann D; Suzuki K; Brereton C; Seddiki N; Sasson SC; Koelsch KK; Landay A; Grey PA; Finlayson R; Kaldor JM; Rosenberg E; Walker BD; Fazekas de St Groth B; Cooper DA; Kelleher AD, 2006, 'Infection of CD127(+) (Interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection', Journal of Virology, vol. 80, pp. 10162 - 10172, http://dx.doi.org/10.1128/JVI.00249-06

Sasson SC; Zaunders J; Zanetti G; King E; Merlin K; Smith DE; Stanley K; Cooper DA; Kelleher AD, 2006, 'Increased plasma interleukin-7 level correlates with decreased CD127 and increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection', Journal of Infectious Diseases, vol. 193, pp. 505 - 514, http://dx.doi.org/10.1086/499309

Seddiki N; Santner-Nanan B; Martinson J; Zaunders J; Sasson SC; Landay A; Solomon MJ; Selby W; Alexander S; Nanan R; Kelleher AD; Fazekas de St Groth B, 2006, 'Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells', Journal of Experimental Medicine, vol. 203, pp. 1693 - 1700, http://dx.doi.org/10.1084/jem.20060468

Fazekos de St Groth B; Seddiki N; Santner-Nanan B; Martinson J; Zaunders J; Sasson SC; Landay A; Nanan R; Kelleher AD, 2006, 'Expression of IL-2 and IL-7 receptors discriminates between human regulatory and activated T-cells within CD45RA and CD45RO compartments', Clinical Immunology, vol. 119, pp. S7 - S7, http://dx.doi.org/10.1016/j.clim.2006.04.010

Sasson SC; Kelleher AD; Cooper DA, 2005, 'The modern ART of HIV infection management: Towards a tailored approach to maximize CD4 T cell reconstitution', Clinical Infectious Diseases, vol. 41, pp. 373 - 375, http://dx.doi.org/10.1086/431489

Sasson SC; Davies S; Chan R; Davies L; Garsia R, 2015, 'IN GOOD CONSCIENCE', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, Vol. 45, pp. 28 - 28, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360834700088&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1