Dr Dorothy Machalek

Latimer RL; Shilling HS; Vodstrcil LA; MacHalek DA; Fairley CK; Chow EPF; Read TRH; Bradshaw CS, 2020, 'Prevalence of Mycoplasma genitalium by anatomical site in men who have sex with men: A systematic review and meta-analysis', Sexually Transmitted Infections, vol. 96, pp. 563 - 570, http://dx.doi.org/10.1136/sextrans-2019-054310

Farnsworth A; Roberts JM; Garland SM; Crescini J; Kaldor JM; Machalek DA, 2020, 'Detection of high-grade cervical disease among women referred directly to colposcopy after a positive HPV screening test varies with age and cytology findings', International Journal of Cancer, vol. 147, pp. 3068 - 3074, http://dx.doi.org/10.1002/ijc.33128

Machalek DA; Tao Y; Shilling H; Jensen JS; Unemo M; Murray G; Chow EPF; Low N; Garland SM; Vodstrcil LA; Fairley CK; Hocking JS; Zhang L; Bradshaw CS, 2020, 'Prevalence of mutations associated with resistance to macrolides and fluoroquinolones in Mycoplasma genitalium: a systematic review and meta-analysis', The Lancet Infectious Diseases, vol. 20, pp. 1302 - 1314, http://dx.doi.org/10.1016/S1473-3099(20)30154-7

Roberts JM; Poynten IM; Molano M; Machalek DA; Hillman RJ; Guzman P; Jin F; Templeton DJ; Fairley CK; Law C; Garland SM; Grulich AE; Cornall AM, 2020, 'Human papillomavirus genotypes in anal high-grade squamous intraepithelial lesion (HSIL): Anal intraepithelial neoplasia grades 2 (AIN2) and 3 (AIN3) are different', Cancer Epidemiology Biomarkers and Prevention, vol. 29, pp. 2078 - 2083, http://dx.doi.org/10.1158/1055-9965.EPI-20-0664

Khawar L; Machalek DA; Regan DG; Donovan B; McGregor S; Guy RJ, 2020, 'Defining elimination of genital warts—a modified delphi study', Vaccines, vol. 8, pp. 1 - 17, http://dx.doi.org/10.3390/vaccines8020316

Murray GL; Bodiyabadu K; Danielewski J; Garland SM; MacHalek DA; Fairley CK; Jensen JS; Williamson DA; Tan LY; Mokany E; Durukan D; Bradshaw CS, 2020, 'Moxifloxacin and Sitafloxacin Treatment Failure in Mycoplasma genitalium Infection: Association with parC Mutation G248T (S83I) and Concurrent gyrA Mutations', Journal of Infectious Diseases, vol. 221, pp. 1017 - 1024, http://dx.doi.org/10.1093/infdis/jiz550

Shilling H; Murray G; Brotherton JML; Hawkes D; Saville M; Sivertsen T; Chambers I; Roberts J; Farnsworth A; Garland SM; Hocking JS; Kaldor J; Guy R; Atchison S; Costa AM; Molano M; Machalek DA, 2020, 'Monitoring human papillomavirus prevalence among young Australian women undergoing routine chlamydia screening', Vaccine, vol. 38, pp. 1186 - 1193, http://dx.doi.org/10.1016/j.vaccine.2019.11.019

Murray GL; Danielewski J; Bradshaw CS; Williamson DA; Birnie J; Su JP; De Petra V; Tan LY; Wee R; MacHalek DA; Read TRH; Garland SM, 2020, 'Performance of the ResistancePlus MG diagnostic test for Mycoplasma genitalium using samples collected with Hologic Aptima Specimen Collection kits', Journal of Medical Microbiology, vol. 69, pp. 244 - 248, http://dx.doi.org/10.1099/jmm.0.001140

Murray GL; Doyle M; Bodiyabadu K; Vodstrcil LA; Garland SM; Danielewski J; Machalek DA; McGuinness C; Plummer EL; de Petra V; Williamson DA; Bradshaw CS, 2020, 'Evaluation of ResistancePlus MG FleXible, a 'near-patient' test for the detection of Mycoplasma genitalium and macrolide resistance mutations, using freshly collected clinical samples', Journal of Medical Microbiology, vol. 70, http://dx.doi.org/10.1099/JMM.0.001271

Chow EPF; Tabrizi SN; Fairley CK; Wigan R; Machalek DA; Regan DG; Hocking JS; Garland SM; Cornall AM; Atchison S; Bradshaw CS; McNulty A; Owen L; Marshall L; Russell DB; Kaldor JM; Chen MY, 2019, 'Prevalence of human papillomavirus in teenage heterosexual males following the implementation of female and male school-based vaccination in Australia: 2014–2017', Vaccine, vol. 37, pp. 6907 - 6914, http://dx.doi.org/10.1016/j.vaccine.2019.09.052

Murray GL; Su JP; Birnie J; Danielewski J; Machalek DA; Bradshaw CS; Read TRH; Costa AM; Garland SM, 2019, 'The impact of sample storage on molecular-based detection of Mycoplasma genitalium', Journal of Applied Microbiology, vol. 127, pp. 1219 - 1223, http://dx.doi.org/10.1111/jam.14359

Drolet M; Bénard É; Pérez N; Brisson M; Ali H; Boily MC; Baldo V; Brassard P; Brotherton JML; Callander D; Checchi M; Chow EPF; Cocchio S; Dalianis T; Deeks SL; Dehlendorff C; Donovan B; Fairley CK; Flagg EW; Gargano JW; Garland SM; Grün N; Hansen BT; Harrison C; Herweijer E; Imburgia TM; Johnson AM; Kahn JA; Kavanagh K; Kjaer SK; Kliewer EV; Liu B; Machalek DA; Markowitz L; Mesher D; Munk C; Niccolai L; Nygård M; Ogilvie G; Oliphant J; Pollock KG; Purriños-Hermida MJ; Smith MA; Steben M; Söderlund-Strand A; Sonnenberg P; Sparen P; Tanton C; Wheeler CM; Woestenberg PJ; Yu BN, 2019, 'Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis', The Lancet, vol. 394, pp. 497 - 509, http://dx.doi.org/10.1016/S0140-6736(19)30298-3

Brotherton JM; Hawkes D; Sultana F; Malloy MJ; Machalek DA; Smith MA; Garland SM; Saville M, 2019, 'Age-specific HPV prevalence among 116,052 women in Australia's renewed cervical screening program: A new tool for monitoring vaccine impact', Vaccine, vol. 37, pp. 412 - 416, http://dx.doi.org/10.1016/j.vaccine.2018.11.075

Murray GL; Danielewski J; Bodiyabadu K; Machalek DA; Bradshaw CS; Costa AM; Birnie J; Garland SM, 2019, 'Analysis of infection loads in Mycoplasma genitalium clinical specimens by use of a commercial diagnostic test', Journal of Clinical Microbiology, vol. 57, http://dx.doi.org/10.1128/JCM.00344-19

Machalek DA; Roberts JM; Garland SM; Thurloe J; Richards A; Chambers I; Sivertsen T; Farnsworth A, 2019, 'Routine cervical screening by primary HPV testing: early findings in the renewed National Cervical Screening Program', Medical Journal of Australia, vol. 211, pp. 113 - 119, http://dx.doi.org/10.5694/mja2.50223

Elder K; Nickson C; Pattanasri M; Cooke S; Machalek D; Rose A; Mou A; Collins JP; Park A; De Boer R; Phillips C; Pridmore V; Farrugia H; Bruce Mann G, 2018, 'Treatment Intensity Differences After Early-Stage Breast Cancer (ESBC) Diagnosis Depending on Participation in a Screening Program', Annals of Surgical Oncology, vol. 25, pp. 2563 - 2572, http://dx.doi.org/10.1245/s10434-018-6469-7

Pattanasri M; Elder K; Nickson C; Cooke S; Machalek D; Rose A; Mou A; Collins JP; Park A; De Boer R; Phillips C; Pridmore V; Farrugia H; Mann GB, 2018, 'Uptake of adjuvant breast cancer treatments recommended by multi-disciplinary meetings', ANZ Journal of Surgery, vol. 88, pp. 745 - 750, http://dx.doi.org/10.1111/ans.14368

Machalek DA; Garland SM; Brotherton JML; Bateson D; McNamee K; Stewart M; Rachel Skinner S; Liu B; Cornall AM; Kaldor JM; Tabrizi SN, 2018, 'Very Low Prevalence of Vaccine Human Papillomavirus Types among 18- to 35-Year Old Australian Women 9 Years Following Implementation of Vaccination', Journal of Infectious Diseases, vol. 217, pp. 1590 - 1600, http://dx.doi.org/10.1093/infdis/jiy075

Cornall AM; Poljak M; Garland SM; Phillips S; Machalek DA; Tan JH; Quinn MA; Tabrizi SN, 2017, 'HPV genotype-specific concordance between EuroArray HPV, Anyplex II HPV28 and Linear Array HPV Genotyping test in Australian cervical samples', Papillomavirus Research, vol. 4, pp. 79 - 84, http://dx.doi.org/10.1016/j.pvr.2017.10.002

Das R; Machalek DA; Molesworth EG; Garland SM, 2017, 'Using Facebook to recruit young Australian men into a cross-sectional human papillomavirus study', Journal of Medical Internet Research, vol. 19, http://dx.doi.org/10.2196/jmir.8739

Garland SM; Machalek DA, 2017, 'Maximizing the impact of human papillomavirus vaccination', Clinical Infectious Diseases, vol. 65, pp. 890 - 892, http://dx.doi.org/10.1093/cid/cix459

Poynten IM; Tabrizi SN; Jin F; Templeton DJ; Machalek DA; Cornall A; Phillips S; Fairley CK; Garland SM; Law C; Carr A; Hillman RJ; Grulich AE, 2017, 'Vaccine-preventable anal human papillomavirus in Australian gay and bisexual men', Papillomavirus Research, vol. 3, pp. 80 - 84, http://dx.doi.org/10.1016/j.pvr.2017.02.003

Jin F; Roberts JM; Grulich AE; Poynten IM; MacHalek DA; Cornall A; Phillips S; Ekman D; McDonald RL; Hillman RJ; Templeton DJ; Farnsworth A; Garland SM; Fairley CK; Tabrizi SN; Law C; Biro C; Richards A; Thurloe J; Adams M; McCaffery K; Howard K; Kelly P; Seeds D; Garcia M; Carr A; Feeney L; Gluyas R; Prestage G; Petoumenos K; Law M; Acraman B; McGrath P; Mellor R; Pezzopane P, 2017, 'The performance of human papillomavirus biomarkers in predicting anal high-grade squamous intraepithelial lesions in gay and bisexual men', AIDS, vol. 31, pp. 1303 - 1311, http://dx.doi.org/10.1097/QAD.0000000000001462

Cornall AM; Poljak M; Garland SM; Phillips S; Tan JH; Machalek DA; Quinn MA; Tabrizi SN, 2017, 'Anyplex II HPV28 detection and Anyplex II HPV HR detection assays are highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities', European Journal of Clinical Microbiology and Infectious Diseases, vol. 36, pp. 545 - 551, http://dx.doi.org/10.1007/s10096-016-2831-5

MacHalek DA; Wark JD; Tabrizi SN; Hopper JL; Bui M; Dite GS; Cornall AM; Pitts M; Gertig D; Erbas B; Garland SM, 2017, 'Genetic and Environmental Factors in Invasive Cervical Cancer: Design and Methods of a Classical Twin Study', Twin Research and Human Genetics, vol. 20, pp. 10 - 18, http://dx.doi.org/10.1017/thg.2016.93

Machalek DA; Chow EPF; Garland SM; Wigan R; Cornall AM; Fairley CK; Kaldor JM; Hocking JS; Williams H; McNulty A; Bell C; Marshall L; Ooi C; Chen MY; Tabrizi SN, 2017, 'Human Papillomavirus Prevalence in Unvaccinated Heterosexual Men after a National Female Vaccination Program', Journal of Infectious Diseases, vol. 215, pp. 202 - 208, http://dx.doi.org/10.1093/infdis/jiw530

Chow EPF; Machalek DA; Tabrizi SN; Danielewski JA; Fehler G; Bradshaw CS; Garland SM; Chen MY; Fairley CK, 2017, 'Quadrivalent vaccine-targeted human papillomavirus genotypes in heterosexual men after the Australian female human papillomavirus vaccination programme: a retrospective observational study', The Lancet Infectious Diseases, vol. 17, pp. 68 - 77, http://dx.doi.org/10.1016/S1473-3099(16)30116-5

Templeton DJ; Roberts JM; Poynten IM; Law C; Hillman RJ; Farnsworth A; Fairley CK; Tabrizi SN; Garland SM; Grulich AE; Jin F; Acraman B; Carr A; Carroll S; Cooper D; Cornall A; Crampton L; Fairley K; Feeney L; Fraissard E; Howard K; Law M; MacHalek D; McCaffery K; McGrath P; Mellor R; Norris R; O'Dwyer M; Pendlebury S; Petoumenos K; Phillips S; Poynten IM; Prestage G; Richards A; Schema L; Seeds D; Segelov E; Thurloe J; Tong W; Varma R, 2017, 'Prevalence and predictors of unsatisfactory anal cytology tests in a cohort of gay and bisexual men in Sydney, Australia: Baseline findings from the Study of the Prevention of Anal Cancer (SPANC)', European Journal of Cancer Prevention, vol. 26, pp. 212 - 216, http://dx.doi.org/10.1097/CEJ.0000000000000321

Machalek DA; Jin F; Poynten IM; Hillman RJ; Templeton DJ; Law C; Roberts JM; Tabrizi SN; Garland SM; Farnsworth A; Fairley CK; Grulich AE; Acraman B; Adams M; Carr A; Carroll S; Cooper D; Cornall A; Crampton L; Ekman D; Feeney L; Fraissard E; Howard K; Law M; McCaffery K; McDonald R; McGrath P; Mellor R; Norris R; O'Dwyer M; Pendlebury S; Petoumenos K; Phillips S; Prestage G; Richards A; Schema L; Seeds D; Segelov E; Thurloe J; Tong W; Varma R, 2016, 'Prevalence and risk factors associated with high-grade anal squamous intraepithelial lesions (HSIL)-AIN2 and HSIL-AIN3 in homosexual men', Papillomavirus Research, vol. 2, pp. 97 - 105, http://dx.doi.org/10.1016/j.pvr.2016.05.003

Roberts JM; Jin F; Thurloe JK; Ekman D; Adams MK; McDonald RL; Biro C; Poynten IM; Grulich AE; Farnsworth A; Aarnsworth R; Acraman B; Adams MK; Carr A; Carroll S; Cooper D; Cornall A; Crampton L; Fairley C; Farnsworth A; Feeney L; Garcia M; Garland S; Gluyas R; Hillman R; Howard K; Lawa F; Law C; Law M; Machalek D; McCaffery K; McDonald RL; McGrath P; Mellor R; Pendlebury S; Petoumenos K; Pezzopane P; Phillips S; Mary Poynten I; Prestage G; Richards A; Roberts JM; Seeds D; Segelov E; Tabrizi S; Templeton D; Tong W; Varma R, 2016, 'The value of a transformation zone component in anal cytology to detect HSIL', Cancer Cytopathology, vol. 124, pp. 596 - 601, http://dx.doi.org/10.1002/cncy.21730

Phillips S; Cornall AM; Machalek DA; Garland SM; Bateson D; Garefalakis M; Tabrizi SN, 2016, 'Comparison of the roche cobas® 4800 HPV assay to roche amplicor for detection of high-risk human papillomavirus', European Journal of Clinical Microbiology and Infectious Diseases, vol. 35, pp. 1305 - 1307, http://dx.doi.org/10.1007/s10096-016-2665-1

Tung ILY; Machalek DA; Garland SM, 2016, 'Attitudes, knowledge and factors associated with Human Papillomavirus (HPV) vaccine uptake in adolescent girls and young women in Victoria, Australia', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0161846

Machalek DA; Poynten IM; Jin F; Hillman RJ; Templeton DJ; Law C; Roberts JM; Tabrizi SN; Garland SM; Farnsworth A; Fairley CK; Grulich AE; Acraman B; Adams M; Carr A; Carroll S; Cooper D; Cornall A; Crampton L; Ekman D; Fairley K; Feeney L; Fraissard E; Howard K; Law M; McCaffery K; McDonald R; McGrath P; Mellor R; Norris R; O'Dwyer M; Pendlebury S; Petoumenos K; Phillips S; Prestage G; Richards A; Schema L; Seeds D; Segelov E; Thurloe J; Tong W; Varma R, 2016, 'A composite cytology-histology endpoint allows a more accurate estimate of anal high-grade squamous intraepithelial lesion prevalence', Cancer Epidemiology Biomarkers and Prevention, vol. 25, pp. 1134 - 1143, http://dx.doi.org/10.1158/1055-9965.EPI-15-1106

Cornall AM; Poljak M; Garland SM; Phillips S; Machalek DA; Tan JH; Quinn MA; Tabrizi SN, 2016, 'EUROarray human papillomavirus (HPV) assay is highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities', European Journal of Clinical Microbiology and Infectious Diseases, vol. 35, pp. 1033 - 1036, http://dx.doi.org/10.1007/s10096-016-2634-8

Poynten IM; Machalek D; Templeton D; Jin F; Hillman R; Zablotzska I; Prestage G; Holt M; Grulich A, 2016, 'Comparison of age-specific patterns of sexual behaviour and anal HPV prevalence in homosexual men with patterns in women', Sexually Transmitted Infections, vol. 92, pp. 228 - 231, http://dx.doi.org/10.1136/sextrans-2015-052032

Hocking JS; Vaughan C; Lau A; MacHelak DA; Graham S, 2016, 'Reducing the burden of sexually transmissible infections in Papua New Guinea requires strengthening of clinical services and engaging men', Sexual Health, vol. 13, pp. 401 - 403, http://dx.doi.org/10.1071/SH16058

Garland SM; Molesworth EG; Machalek DA; Cornall AM; Tabrizi SN, 2015, 'How to best measure the effectiveness of male human papillomavirus vaccine programmes?', Clinical Microbiology and Infection, vol. 21, pp. 834 - 841, http://dx.doi.org/10.1016/j.cmi.2015.05.038

Cornall AM; Roberts JM; Molano M; Machalek DA; Phillips S; Hillman RJ; Grulich AE; Jin F; Poynten IM; Templeton DJ; Garland SM; Tabrizi SN, 2015, 'BMJ open: Laser capture microdissection as a tool to evaluate human papillomavirus genotyping and methylation as biomarkers of persistence and progression of anal lesions', BMJ Open, vol. 5, http://dx.doi.org/10.1136/bmjopen-2015-008439

Machalek DA; Grulich AE; Hillman RJ; Jin F; Templeton DJ; Tabrizi SN; Garland SM; Prestage G; McCaffery K; Howard K; Tong W; Fairley CK; Roberts J; Farnsworth A; Poynten IM, 2013, 'The Study of the Prevention of Anal Cancer (SPANC): Design and methods of a three-year prospective cohort study', BMC Public Health, vol. 13, http://dx.doi.org/10.1186/1471-2458-13-946

Grulich AE; Poynten IM; MacHalek DA; Jin F; Templeton DJ; Hillman RJ, 2012, 'The epidemiology of anal cancer', Sexual Health, vol. 9, pp. 504 - 508, http://dx.doi.org/10.1071/SH12070

Grulich AE; Machalek DA; Poynten IM; Jin F; Fairley CK; Tabrizi SN; Garland SM; Templeton DJ; Hillman RJ, 2012, 'Anal cancer screening Reply', LANCET ONCOLOGY, vol. 13, pp. E280 - E280, http://dx.doi.org/10.1016/S1470-2045(12)70272-3

Grulich AE; Machalek DA; Poynton IM; Jin F; Fairley CK; Tabrizi S; Garland S; Templeton DJ; Hillman R, 2012, 'Anal cancer screening - Authors' reply', Lancet Oncology, vol. 13, pp. E280, http://dx.doi.org/10.1016/S1470-2045(12)70272-3

Machalek DA; Poynten IM; Jin F; Fairley CK; Farnsworth A; Garland S; Hillman R; Petoumenos K; Roberts J; Tabrizi S; Templeton DJ; Grulich AE, 2012, 'Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: A systematic review and meta-analysis', Lancet Oncology, vol. 13, pp. 487 - 500, http://dx.doi.org/10.1016/S1470-2045(12)70080-3

Machalek DA; Grulich AE; Jin F; Templeton DJ; Poynton IM, 2012, 'The epidemiology and natural history of anal human papillomavirus infection in men who have sex with men', Sexual Health, vol. 9, pp. 527 - 537, http://dx.doi.org/10.1071/SH12043

O'Toole S; Machalek DA; Shearer R; Millar E; Nair R; Schofield PR; McLeod D; Cooper CE; Mcneil CM; Mcfarland A; Nguyen A; Ormandy CJ; Qiu M; Rabinovich B; Martelotto L; Vu D; Hannigan GE; Musgrove EA; Christ DU; Sutherland RL; Watkins DJ; Swarbrick A, 2011, 'Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer', Cancer research, vol. 71, pp. 4002 - 4014, http://dx.doi.org/10.1158/0008-5472.CAN-10-3738

O'Toole SA; Machalek D; Shearer R; Millar EKA; Nair R; Martelotto L; McLeod D; Cooper C; Qiu MR; Sutherland RL; Watkins DN; Swarbrick A, 2010, 'Hedgehog Ligand Overexpression Predicts Poor Outcome in Breast Cancer and Is a Potential Therapeutic Target for Metastatic Disease', CANCER RESEARCH, vol. 70, http://dx.doi.org/10.1158/0008-5472.SABCS10-S6-8

Lawson VA; Lumicisi B; Welton J; Machalek D; Gouramanis K; Klemm HM; Stewart JD; Masters CL; Hoke DE; Collins SJ; Hill AF, 2010, 'Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein', PLoS ONE, vol. 5, http://dx.doi.org/10.1371/journal.pone.0012351

Molano M; Tabrizi SN; Garland SM; Roberts JM; MacHalek DA; Phillips S; Chandler D; Hillman RJ; Grulich AE; Jin F; Poynten IM; Templeton DJ; Cornall AM; McCaffery K; Howard K; Farnsworth A; Fairley K; Prestage G; Carr A; Tong W; Law C; Acraman B; Crampton L; Feeney L; Fraissard E; Law M; McGrath P; Mellor R; Norris R; O'Dwyer M; Pendlebury S; Petoumenos K; Richards A; Schema L; Seeds D; Segelov E; Thurloe J; Varma R, 2010, 'CpG methylation analysis of hpv16 in laser capture microdissected archival tissue and whole tissue sections from high grade anal squamous intraepithelial lesions: A potential disease biomarker', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0160673

Tanudji M; Machalek D; Arndt GM; Rivory L, 2010, 'Competition Between siRNA Duplexes: Impact of RNA-Induced Silencing Complex Loading Efficiency and Comparison Between Conventional-21 bp and Dicer-Substrate siRNAs', Oligonucleotides, vol. 20, pp. 27 - 32, http://dx.doi.org/10.1089/oli.2009.0195

Lawson VA; Vella LJ; Stewart JD; Sharples RA; Klemm H; Machalek DM; Masters CL; Cappai R; Collins SJ; Hill AF, 2008, 'Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture', International Journal of Biochemistry and Cell Biology, vol. 40, pp. 2793 - 2801, http://dx.doi.org/10.1016/j.biocel.2008.05.024