Manifestations ranging from asymptomatic to severe illnesses may be explained by genetic variations in host and pathogen genomes. This work explored: 1) the interaction of SNPs in inflammatory genes and the severity of acute infections, 2) the viral determinants of plasma leakage in dengue, and 3) the host immunological footprint on dengue genomes.
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Dr Braulio Mark Valencia Arroyo Braulio Mark Valencia Arroyo is an infectious disease physician experienced in basic and clinical aspects of neglected tropical diseases. As a PhD student and postdoctoral researcher, he is exploring the host genomic determinants of specific clinical phenotypes, including naturally resistant individuals, severe acute illnesses, and protracting post-infectious manifestations irrespectively of the pathogen. |
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