About the Project
In 2009, the world experienced the first pandemic of influenza in 40 years; the rationale for this observational study of patients hospitalised with all types of influenza is to understand better the risk factors for severe infection and poor outcomes with influenza.
To characterise and describe the outcomes over a 60-day follow-up period of those with influenza -- who are hospitalized with severe and/or complicated influenza
Ongoing with 657 participants enrolled globally
The data gathered will help us understand the characteristics and outcomes over a 60-day follow-up period of participants with influenza – including pandemic 2009 H1N1who are hospitalized with severe and/or complicated influenza in geographically diverse locations. Specific objectives are to estimate the percentage of patients who die, to obtain information on risk factors for mortality, and to establish a central repository of specimens for use in virus characterization, including subtyping, antigenic and genetic analyses, identification of signature mutations associated with antiviral drug resistance, mutational evolution, and additional reassortment. This information will be used to guide policymakers and to design future studies.
Conference abstracts have been presented.
Clinical Project Leader
Ph +61 (2) 9385 0908
Dr Sarah Pett, Professor Dominic Dwyer, Dr John McBride, Professor Jenny Hoy and Dr Julian Elliott.
Project Collaborators: External
TVRP is also responsible for coordinating the study in Thailand (2 sites), Hong Kong (1 site), Argentina (8 sites), and Chile (2 site).