FLU 002 Plus (Respiratory Virus Outpatient Study) - An International Observational Study to Characterize Adults with Influenza or Other Targeted Respiratory Viruses

Date Commenced:
09/2009
Project Status
Ongoing
Expected Date of Completion:
12/2014
Project Supporters

University of Minnesota; NIAID, USA

Currently recruiting
Yes
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About the Project

Rationale

In 2009, the world experienced the first pandemic of influenza in 40 years; the rationale for this observational study is to understand better the types of presentation and risk factors for severe infection with all types of influenza.

Aims

The purpose of this observational study is to describe participants in geographically diverse locations with influenza virus infection and their clinical course over a 14-day period following enrolment.

Design & Method

Observational

Progress/Update

Ongoing, globally 2194 participants enrolled

Benefits

Further our understanding of risk factors for disease severity; and to establish a central repository of specimens for use in virus characterization, including subtyping, antigenic and genetic analyses, identification of signature mutations associated with antiviral drug resistance, mutational evolution, and additional reassortment. This information will be used to guide policymakers and to design future studies.

Output

Abstracts at conferences have been presented

Project Members
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Clinical Project Leader
Ph +61 (2) 9385 0908
Project Attachment
Other Investigators

Professor Dominic Dwyer, Dr Richard Moore, Dr Tuck Meng Soo, Dr Norm Roth, Dr Mark Bloch

Project Collaborators: External

St. Vincent’s Hospital, Westmead Hospital, Interchange General Practice, Northside Clinic, Prahran Market Clinic, Taylor Square Private Clinic, Holdsworth House Medical Practice;

Westmead Hospital

Interchange General Practice

Northside Clinic

Prahran Market Clinic

Holdsworth House Medical Practice

TVRP is also responsible for coordinating the study in Thailand (2 sites), Argentina (10 sites), and Chile (2 sites)

Project Research Area

Project Contacts

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