The Australian HIV Observational Database (AHOD)

Date Commenced:
12/1999
Project Status
Ongoing
Expected Date of Completion:
Ongoing
Project Supporters

Foundation for AIDS Research (amfAR) via a US National Institutes of Health grant through the International Epidemiologic Databases Evaluating AIDS collaboration; consortium of pharmaceutical companies.

Currently recruiting
Yes
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About the Project

The Australian HIV Observational Database (AHOD) is an observational cohort study of HIV infected individuals attending specialised general practitioner sites, sexual health clinics and tertiary referral centres throughout Australia. This study has been ongoing since 1999, and currently has 29 active sites, total of 4125 patients enrolled with average 7 years of follow-up data from Australia and New Zealand.

The primary objectives of the Australian HIV Observational Database are to monitor patterns of antiretroviral treatment use, including the efficacy of different treatment regimens, related to demographic factors and markers of HIV disease stage; patterns of toxicities/adverse events associated with antiretroviral treatment use, as well as to monitor HIV related and non-HIV related causes of death.

The core data collected include patient demographics, HIV disease stage (CD4 t-cell counts, HIV viral load and AIDS defining illness), as well as antiretroviral treatment, and laboratory data (including total cholesterol, HDL, haemoglobin, ALT and AST). Data are contributed to AHOD in electronic form from computerised patient management systems on a six monthly basis in agreed standardised formats. Data are merged, collated and summarised on the behalf of contributing sites at The Kirby Institute UNSW, Sydney.

Summary reports of trends in antiretroviral treatment use are published on a yearly basis, and widely circulated in Australia. Summary data are also contributed to the Australian Annual Surveillance Report. Peer-reviewed articles have also been published. Reports and publication abstracts can be downloaded from the links below.

The Australian HIV Observational Database is funded as part of the Asia Pacific HIV Observational Database, a program of The Foundation for AIDS Research, amfAR, and is supported in part by a grant from the U.S. National Institutes of Health’s National Institute of Allergy and Infectious Diseases (NIAID) (Grant No. U01-AI069907) and by unconditional grants from Merck Sharp & Dohme; Gilead; Bristol-Myers Squibb; Boehringer Ingelheim;  Janssen-Cilag; ViiV Healthcare . The Kirby Institute is funded by The Australian Government Department of Health and Ageing, and is affiliated with the Faculty of Medicine, UNSW Australia.

Study Coordinators: Rainer Puhr
Administrative Coordinator: Erin Ogilvie
Study Leader: Kathy Petoumenos

Principal Investigator: Matthew Law

Project Members
image - 1338340968 Matthew Law.jpg
Professor and Program Head
Ph (02) 93850966
image - Rainer 220415
Statistician
Ph 02 9385 0967
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Data Administrator
Ph 02 93850994
Other Investigators

AHOD COLLABORATORS

New South Wales

  • Tamworth Sexual Health, Tamworth
  • Blue Mountains Sexual Health and HIV Clinic, Katoomba
  • Holdsworth House Medical Practice, Darlinghurst
  • Illawarra Sexual Health, Warrawong
  • Royal Prince Alfred Sexual Health, Camperdown
  • Nepean Sexual Health and HIV Clinic, Penrith
  • Holden Street Clinic, Gosford
  • Lismore Sexual Health & AIDS Services, Lismore
  • Sydney Sexual Health Centre, Sydney
  • St Vincent's Hospital, Darlinghurst
  • Taylor Square Private Clinic, Darlinghurst
  • Dr Ellis, General Medical Practice, Coffs Harbour
  • East Sydney Doctors, Darlinghurst
  • Albion Street Clinic, darlinghurst
  • Western Sydney Sexual Health Clinic

Northern Territory

  • Communicable Disease Centre, Royal Darwin Hospital, Darwin

South Australia

  • The O’Brien Street Clinic, Adelaide

Queensland

  • Sexual Health and HIV Service in Metro North, Brisbane
  • Clinic 87, Blackall Terrace
  • Gladstone Road Medical Centre, Highgate Hill
  • Gold Coast Sexual Health Clinic, Miami
  • Cairns Sexual Health Clinic, Cairns

Victoria

  • Melbourne Sexual Health Centre, Carlton
  • Prahran Market Clinic, Prahran
  • The Alfred Hospital, Prahran
  • Northside Clinic, North Fitzroy
  • Monash Medical Centre, Clayton

Western Australia

  • Department of Clinical Immunology, Royal Perth Hospital, Perth

New Zealand

  • Wellington Hospital, Wellington
  • Waikato District Hospital, Hamilton
Project Coordinators
image - Rainer 220415
Statistician
Ph 02 9385 0967

Project Contacts

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