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Understanding malaria infection and treatment in human clinical trials

Project Status: Ongoing
This work aims to develop our understanding of malaria infection and treatment during human infection. We analyse data collected from a unique series...
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Understanding Neonatal Immunity

Project Status: Ongoing
Newborns are very susceptible to infection compared to adults, and also have lower responses to some vaccines.  One important type of cell which can...
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Understanding the factors that shape the T cell receptor repertoire

Project Status: Ongoing
Effective T cell recognition and immune control of infection depend on the availability of a diverse and well-balanced repertoire of T cell receptors...
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Understanding the impact of development, age, and chronic infection on the T cell repertoire

Project Status: Ongoing
Effective T cell recognition and immune control of infection depend on the availability of a diverse and well-balanced repertoire of T cell receptors...
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Understanding the interactions of Epstein-Barr virus and malaria infection

Project Status: Ongoing
Burkitt lymphoma was first discovered in 1958, and is the most common childhood cancer in equatorial Africa. Infection with both Epstein-Barr virus (...
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Understanding the role of T cell repertoire composition in T cell responses to infection and vaccination.

Project Status: Ongoing
Effective T cell recognition and immune control of infection depend on the availability of a diverse and well-balanced repertoire of T cell receptors...
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Unprotected oral sex and sex workers at Sydney Sexual Health Centre

Project Status: Ongoing
Unprotected fellatio at work may represent a risk for STI acquisition in the oropharynx, and subsequent onwards transmission. This study seeks to...
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Using mathematical models to assess the impact of interventions to reduce sexually transmitted infections in Australia

Project Status: Completed
This research involves the design, implementation and analysis of mathematical models for assessing the health economic impact of public health...
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Using mouse models to understand malaria infection, treatment and immunity

Project Status: Ongoing
In malaria infection both drug treatment and host immune responses are known to be able to reduce parasite numbers and often completely “clear” the...
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VE Substudy of main MARCH study

Project Status: Completed
Maraviroc Switch vascular endothelium (VE) substudy:a substudy of MARCH, a randomised, open‐label study to evaluate the efficacy and safety of...

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